Publications 1990-99  
 
97. Santos, L.M.B., Lider, O., Audette, J., Khoury, S.J., and H.L. Weiner: Characterization of immunomodulatory properties and accessory cell function of small intestinal epithelial cells. Cell. Immunol. 127: 26–34, 1990.

98. Nussenblatt, R.B., Caspi, R.R., Mahdi, R., Chan, C.C., Roberge, F., Lider, O., and H.L. Weiner: Inhibition of S antigen induced experimental autoimmune uveoretinitis by oral induction of tolerance with S antigen. J. Immunol. 144: 1689–1695, 1990.

99. Wucherpfennig, W., Ota, K., Endo, N., Seidman, J.G., Rossenzweig, A., Weiner, H.L., and D.A. Hafler: Shared human T cell receptor V usage to immunodominant regions of myelin basic protein. Science 248: 1016–1020, 1990.

100. Ota, K., Matsui, M., Milford, E.L., Mackin, G.A., Weiner, H.L., and D.A. Hafler: T cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 346: 183–187, 1990.

101. Toms, R., Weiner, H.L., and D. Johnson: Identification of IgE positive cells and mast cells in frozen sections of multiple sclerosis brains. J. Neuroimmunol. 30: 169–177, 1990.

102. Zhang, Z. Jenny, Lee, C.S.Y., Lider, O., and H.L. Weiner: Suppression of adjuvant arthritis in Lewis rats by oral administration of type II collagen. J. Immunol. 145: 2489–2493, 1990.

103. Khoury, S.J., Lider, O., Al Sabbagh, A., and H.L. Weiner: Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein III. Synergistic effect of lipopolysaccharide. Cell. Immunol. 131: 302–310, 1990.

104. Hafler, D.A., Orav, J., Gertz, R., Stazzone, L., and H.L. Weiner: Immunologic effects of cyclophosphamide/ACTH in patients with chronic progressive multiple sclerosis. J. Neuroimmunol. 32: 149–158, 1991.

105. Hafler, D.A., Chofflon, M., Kurt Jones, E., and H.L. Weiner: IL 1 corrects the defective autologous mixed lymphocyte response in multiple sclerosis. Clin. Immunol. Immunopathol. 58: 115–125, 1991.

106. Lee, S.J., Wucherpfennig, K.W., Brod, S.A., Benjamin D., Weiner, H.L., and D.A. Hafler: Common T cell receptor V usage in oligoclonal T lymphocytes derived from cerebrospinal fluid and blood of patients with multiple sclerosis. Ann. Neurol. 29: 33–40, 1991.

107. Brod, S.A., Al Sabbagh, A., Sobel, R.A., Hafler, D.A., and H.L. Weiner: Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin antigens IV. suppression of chronic relapsing disease in the Lewis rat and strain 13 guinea pig. Ann. Neurol. 29: 615–622, 1991.

108. Lider, O., Miller, A., Miron, S., Hershkoviz, R., Weiner, H.L., Zhang, X., and E. Heber Katz: Non encephalitogenic CD4 CD8 V2V8.2+ anti myelin basic protein rat T lymphocytes inhibit disease induction. J. Immunol. 147: 1208–1213, 1991.

109. Miller, A., Lider, O., and H.L. Weiner: Antigen driven bystander suppression following oral administration of antigens. J. Exp. Med. 174: 791–798, 1991.

110. Zhang, Z.J., Davidson, L., Eisenbarth, G., and H.L. Weiner: Suppression of diabetes in NOD mice by oral administration of porcine insulin. Proc. Natl. Acad. Sci. USA 88: 10252–10256, 1991.

111. Zamaroczy, D., Schluesener, H.J., Jolesz, F.A., Sobel, R.A., Colucci, V.M., Weiner, H.L., and T. Sandor: Differentiation of experimental white matter lesions using multiparametric magnetic resonance measurements. Invest. Radiol. 26: 317–324, 1991.

112. Sayegh, M.H., Zhang, Z.J., Hancock, W.W., Kwok, C.A., Carpenter, C.B., and H.L. Weiner:Downregulation of the immune response to histocompatibility antigens and prevention of sensitization to skin allografts by orally administered alloantigen. Transplantation 53: 163–166, 1992.

113. Miller, A., Lider, O., Roberts, A.B., Sporn, M.B., and H.L. Weiner: Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of TGF  following antigen specific triggering. Proc. Natl. Acad. Sci. USA 89: 421–425, 1992.

114. Hafler, D.A., Cohen, I., Benjamin, D.S., and H.L. Weiner: T cell vaccination in multiple sclerosis: a preliminary report. Clin. Immunol. Immunopathol. 62: 307–313, 1992.

115. Miller, A., Lider, O., Al-Sabbagh, A., and H.L. Weiner: Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. V. Hierarchy of suppression by myelin basic protein from different species. J. Neuroimmunol. 39: 243–250, 1992.

116. Sayegh, M.H., Khoury, S.J., Hancock, W.W., Weiner, H.L., and C.B. Carpenter: Induction of immunity and oral tolerance with polymorphic class II MHC allopeptides in the rat. Proc. Natl. Acad. Sci. USA 89: 7762–7766, 1992.

117. Khoury, S.J., Hancock, W.W., and H.L. Weiner: Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of TGF , IL 4, and prostaglandin E expression in the brain. J. Exp. Med. 176: 1355–1364, 1992.

118. Weiner, H.L., Mackin, G.A., Orav, E.J., Hafler, D.A., Dawson, D.M., LaPierre, Y., Herndon, R., Lehrich, J.R., Hauser, S.L., Turel, A., Fisher, M., Birnbaum, G., McArthur, J., Butler, R., Moore, M., Sigsbee, B., Safran, A., and the Northeast Cooperative Multiple Sclerosis Treatment Group: Intermittent cyclophosphamide pulse therapy in progressive multiple sclerosis: final report of the Northeast Cooperative Multiple Sclerosis Treatment Group. Neurology 43: 910–918, 1993.

119. Hancock, W.W., Sayegh, M.H., Kwok, C.A., Weiner, H.L., and C.B. Carpenter: Oral but not intravenous alloantigen prevents accelerated allograft rejection by selective intragraft TH2 cell activation. Transplantation 55(5): 1112–1118, 1993.

120. Weiner, H.L., Mackin, G.A., Matsui, M., Orav, E.J., Khoury, S.J., Dawson, D.M., and D.A. Hafler: Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis. Science 259: 1321–1324, 1993.

121. Khoury, S.J., Sayegh, M.H., Hancock, W.W., Gallon, L., Carpenter, C.B., and H.L. Weiner: Acquired tolerance to experimental autoimmune encephalomyelitis by intrathymic injection of myelin basic protein or its major encephalitogenic peptide. J. Exp. Med. 178: 559–566, 1993.

122. Miller, A., Zhang, Z.J., Sobel, R.A., Al-Sabbagh, A., and H.L. Weiner: Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. VI. Suppression of adoptively transferred diseases and differential effects of oral vs. intravenous tolerization. J. Neuroimmunol. 46: 73–82, 1993.

123. Abromson-Leeman, S., Hayashi, M., Martin, C., Sobel, R., Al-Sabbagh, A., Weiner, H.L., and M.E. Dorf: T cell responses to myelin basic protein in experimental autoimmune encephalomyelitis-resistant BALB/c mice. J. Neuroimmunol. 45: 89–102, 1993.

124. Trentham, D.E., Dynesius-Trentham, R.A., Orav, E.J., Combitchi, D. Lorenzo, C., Sewell, K.L., Hafler, D.A., and H.L. Weiner: Effects of oral administration of type II collagen on rheumatoid arthritis. Science 261: 1727–1730, 1993.

125. Miller, A., Al-Sabbagh, A., Santos, L.M.B., Prabhu Das, M., and H.L. Weiner: Epitopes of myelin basic protein that trigger TGF  release following oral tolerization are distinct from encephalitogenic epitopes and mediate epitope driven bystander suppression. J. Immunol. 151: 7307–7315, 1993.

126. Zhang, J., Markovic, S., Raus, J., Lacet, B., Weiner, H.L., and D.A. Hafler: Increased frequency of IL 2 responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J. Exp. Med. 179: 973–984, 1993.

127. Miller, A., Lider, O., Abramsky, O., and H.L. Weiner: Orally administered myelin basic protein in neonates primes for immune responses and enhances experimental autoimmune encephalomyelitis in adult animals. Eur. J. Immunol. 24: 1026–1032, 1994.

128. Friedman, A., and H.L. Weiner: Induction of anergy or active suppression following oral tolerance is determined by antigen dosage. Proc. Natl. Acad. Sci. USA 91: 6688–6692, 1994.

129. Kuchroo, V.K., Collins, M., Al-Sabbagh, A., Sobel, R.A., Whitters, M.J., Zamvil, S.S., Dorf, M.E., Hafler, D.A., Seidman, J.G., Weiner, H.L., and I.J. Rimm: T cell receptor usage determines disease susceptibility in experimental autoimmune encephalomyelitis. J. Exp. Med. 179: 1659–1664, 1994.

130. Khoury, S.J., Guttman, C.R.G., Orav, E.J., Hohol, M.J., Ahn, S.S., Hsu, L., Kikinis, R., Jolesz, F. A., and H.L. Weiner: Longitudinal MRI imaging in multiple sclerosis: Correlation between disability and lesion burden. Neurology 44: 2120–2124, 1994.

131. Al-Sabbagh, A., Miller, A., Santos, L.M.B., and H.L. Weiner: Antigen driven tissue-specific suppression following oral tolerance: Orally administered myelin basic protein suppresses proteolipid induced experimental autoimmune encephalomyelitis in the SJL mouse. Eur. J. Immunol. 24: 2104–2109, 1994.

132. Santos, L.M.B., Al-Sabbagh, A., Londono, A., and H.L. Weiner: Oral tolerance to myelin basic protein induces regulatory TGF  secreting T cells in Peyer's patches of SJL mice. Cell. Immunol. 157: 439–447, 1994.

133. Chen, Y., Kuchroo, V.K., Inobe, J., Hafler, D. A., and H.L. Weiner: Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis. Science 265: 1237–1240, 1994.

134. Zamvil, S.S., Al-Sabbagh, A., Nelson, P.A., Kaul, D., St. Charles, M., Mitchell, D.J., Steinman, L., Weiner, H.L., and V.K. Kuchroo: 'Lupus-prone' mice are susceptible to organ-specific autoimmune disease, experimental allergic encephalomyelitis. Pathobiology 62: 113–119, 1994.

135. Fishman-Lobell, J., Friedman, A., and H.L. Weiner: Different kinetic patterns of cytokine gene expression in vivo in orally tolerized mice. Eur. J. Immunol. 24: 2720–2724, 1994.


136. Hohol, M.J., Orav, E.J., and H.L. Weiner: Disease steps in multiple sclerosis: A simple approach to evaluate disease progression. Neurology 45: 251–255, 1995.

137. Kuchroo, V.J., Prabhu Das, M., Brown, J.A., Ranger, A.M., Zamvil, S.S., Sobel, R.A., Weiner, H.L., Nabavi, N., and L.H. Grimcher: B7-1 and B7-2 costimulatory molecules differentially activate the TH1/TH2 developmental pathways: Application to autoimmune disease therapy. Cell 80: 707–718, 1995.

138. Prabhu Das, M.R., Zamvil, S.S., Boriello, F., Weiner, H.L., Sharpe, A.H., and V.K. Kuchroo: Reciprocal expression of co-stimulatory molecules, B7-1 and B7-2, on murine T cells following activation. Eur. J. Immunol. 25: 207–211, 1995.

139. Balashov, K.E., Khoury, S.J., Hafler, D.A., and H.L. Weiner: Inhibition of T cell responses by activated human CD8+ T cells is mediated by IFN- and is defective in chronic progressive multiple sclerosis. J. Clin. Invest. 95: 2711–2719, 1995.

140. Chen, Y., Inobe, J., and H.L. Weiner: Induction of oral tolerance to myelin basic protein in CD-8 depleted mice: both CD4+ and CD8+ T cells mediate active suppression. J. Immunol. 1565: 910–916, 1995.

141. Chen, Y., Inobe, J., Marks, R., Gonnella, P., Kuchroo, V.J., and H.L. Weiner: Peripheral deletion of antigen-reactive T cells in oral tolerance. Nature 376: 177–180, 1995.

142. Yoshino, S., Quattrocchi, E., and H.L. Weiner: Suppression of antigen-induced arthritis in Lewis rats by oral administration of type II collagen. Arthritis Rheum. 38: 1092–1096, 1995.

143. Khoury, S.J., Gallon, L., Chen, W., Betres, K., Russell, M.E., Hancock, W.W., Carpenter, C.B., Sayegh, M.H., and H.L. Weiner: Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: Thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo. J. Exp. Med. 182: 357–366, 1995.

144. Hancock, W.W., Polanski, M., Zhang, J., Blogg, N., and H.L. Weiner: Suppression of insulitis in NOD mice by oral insulin administration is associated with selective expression of IL 4, IL 10, TFG  and prostaglandin-E. Amer. J. Path. 147: 1193–1199, 1995.

145. Chen, Y., Kuchroo, V.K., Inobe, J-I., Baron, J., Janeway, C., and H.L. Weiner: Oral tolerance in myelin basic protein T cell receptor transgenic mice: Suppression of autoimmune encephalomyelitis and dose dependent induction of regulatory cells. Proc. Natl. Acad. Sci. USA 93: 388–391, 1996.

146. Fukaura, H., Kent, S.C., Pietrusewicz, M.J., Khoury, S.J., Weiner, H.L., and D.A. Hafler: Induction of circulating myelin basic protein and proteolipid protein specific TGF 1 secreting Th3 cells by oral administration of myelin in multiple sclerosis patients. J. Clin. Invest. 98: 70–77, 1996.

147. Melamed, D., Fishman-Lobell, J., Uni, Z., Weiner, H.L., and Aharon Friedman: Peripheral tolerance of TH2 lymphocytes induced by continuous feeding of ovalbumin. Int. Immunol. 8(5): 717–724, 1996.

148. Al-Sabbagh, A., Nelson, P., Sobel, R.A., and H.L. Weiner: Antigen driven peripheral immune tolerance: suppression of experimental autoimmune encephalomyelitis and collagen induced arthritis by aerosol administration of myelin basic protein or type II collagen. Cell. Immunol. 171: 111–119, 1996.

149. Al-Sabbagh, A.M., Goad, M.E.P., Weiner, H.L., and P.A. Nelson: Decreased CNS inflammation and absence of clinical exerbation of disease after six months oral administration of bovine myelin in diseased SJL/J Mice with chronic relapsing experimental autoimmune encephalomyelitis, J. Neurosci. Res. 45: 424–429, 1996.

150. Encinas, J.A., Lees, M.B., Sobel, R.A., Symonowicz, C., Greer, J.M., Shovlin, C.L., Weiner, H.L., Seidman, C.E., Seidman, J.G., and V.K. Kuchroo: Genetic analysis of susceptibility to experimental autoimmune encephalophalomyein a cross between SJL/J and B10.S mice. J. Immunol. 157: 2186–2192, 1996.

151. Balashov, K.E., Smith, D.R., Khoury, S.J., Hafler, D.A., and H.L. Weiner: Increased IL 12 production in progressive multiple sclerosis: Induction by activated CD4+T cells via CD40 ligand. Proc. Natl. Acad. Sci. USA 94: 599–603, 1997.

152. Chen., Y., Inobe, J-I., and H.L. Weiner: Inductive events in oral tolerance in the TCR transgenic adoptive transfer model. Cell. Immunol. 178: 62–69, 1997.

153. Nussenblatt, R.B., Gery, I., Weiner, H.L., Ferris, F., Shiloach, J., Ramaley, N., Perry, C., Caspi, R., Hafler, D., Foster, S., and S.M. Whitcup: Treatment of uveitis by oral administration of retinal antigens: Results of a phase I/II randomized masked trial. Am. J. Ophthalmol. 123: 583–592, 1997.

154. Polanski, M., Melican, N., Zhang, J., and H.L. Weiner. Oral administration of the immunodominant B-chain of insulin reduces diabetes in a co-transfer model of diabetes in the NOD mouse and is associated with a switch from Th1 to Th2 cytokines. J. Autoimmun. 10(4): 339–346, 1997.

155. Hohol, M.J., Guttmann, C.R.G., Orav, E.J., Mackin, G.A., Kikinis, R., Khoury, S.J., Jolesz, F.A., and H.L. Weiner: Serial neuropsychological assessment and MRI analysis in multiple sclerosis. Arch. Neurol. 54: 1018–1025, 1997.

156. Smith, D.R., Balashov, K.E., Hafler, D.A., Khoury, S.J., and H.L. Weiner: Immune deviation following pulse cyclophosphamide treatment of multiple sclerosis: increased IL 4 production and associated eosinophilia. Ann. Neurol. 42: 313–318, 1997.

157. Chen, Y., Hancock, W., Marks, R., Gonnella, P.A., and H.L. Weiner: Mechanisms of recovery from experimental allergic encephalomyelitis: T cell deletion and immune deviation in myelin basic protein T cell receptor transgenic mice. J. Neuroimmunol. 82: 149–159, 1998.

158. Samoilova, E.B., Horton, J.L., Zhang, H., Khoury, S.J., Weiner, H.L., and Y. Chen: CTLA-4 is required for the induction of high dose oral tolerance. Int. Immunol. 10: 491–498, 1998.

159. Maron, R., Palanivel, V., Weiner, H.L., and D.A. Harn: Oral administration of insulin B-chain and schistosome egg antigens generates and enhances Th2-type responses in NOD mice. Clin. Immunol. Immunopathol. 87: 85–92, 1998.

160. Gonnella, P.A., Chen, Y., Inobe, J.-I., Quartulli, M., and H.L. Weiner: In situ immune response in gut-associated lymphoid tissue (GALT) following oral antigen in TcR-transgenic mice. J. Immunol. 160: 4706–4718, 1998.

161. Comabella, M., Balashov, K., Issazadeh, S., Smith, D., Weiner, H.L., and S.J. Khoury: Elevated IL 12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy. J. Clin. Invest. 102: 671–678, 1998.

162. Inobe, J.-I., Slavin, A., Komagata, Y., Chen Y., Liu, L., and H.L. Weiner: IL 4 is a differentiation factor for TGF-b secreting Th3 cells and oral administration of IL 4 enhances oral tolerance in experimental allergic encephalomylitis. Eur. J. Immunol. 28: 2780–2790, 1998.

163. Takashima, H., Smith, D.R., Fukara, H., Khoury, S.J., Hafler, D.A., and H.L. Weiner: Pulse cyclophosphamide plus methylprednisolone induces myelin-antigen-specific IL 4 secreting T cells in multiple sclerosis patients. Clin. Immunol. Immunopathol. 88: 28–34, 1998.

164. Liu, L, Rich, B.E., Inobe, J-I, Chen, W., and H.L. Weiner: Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL 10 prime naïve CD4+ T cells to secrete IL 4. Int. Immunol. 10: 1017–1026, 1998.

165. Bettelli, E., Pabhu-Das, M., Howard, E.D., Weiner, H.L., Sobel, R.A., and V.K. Kuchroo: IL 10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL 10- and IL 4-deficient and transgenic mice. J. Immunol. 161: 3299–3306, 1998.

166. Balashov, K.E., Olek, M.J., Khoury, S.J., and H.L. Weiner: Seasonal variation of IFN-g production in progressive multiple sclerosis. Ann. Neurol. 44: 824–828, 1998.

167. Windhagen, A., Anderson, S.E., Carrizosa, A., Balashov, K., Weiner, H.L., and D.A. Hafler: Cytokine secretion of myelin basic protein reactive T cells in patients with multiple sclerosis. J. Neuroimmunol. 91(1–2): 1–9, 1998.

168. Chen, W., Weiner, H.L., and S. Wahl: Oral delivery of group A streptococccal cell walls augments circulating TGF-b and suppresses SCW arthritis. J. Immunol. 161(11): 6297-6304, 1998.

169. Kappos, L., Moeri, D., Radue, E. W., Schoetzau, A., Schweikert, K., Barkhof, F., Miller, D., Guttmann, C. R. G., Weiner, H. L., Gasperini, C. and Filippi, M. f. t. G. M. M.-a. G. Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and change in disability or impairment in multiple sclerosis: a meta-analysis. Lancet 353:964-969, 1999

170. Encinas, J.A., Wicker, L.S., Peterson, L.B., Mukasa, A., Teuscher, C., Sobel, R., Weiner, H.L., Seidman, C.E., Seidman, J.G. and V.K. Kuchroo: QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing 1IL2. Nature Genetics, 21:158-160, 1999.

171. Guttmann, C.R.G., Kikinis, R., Anderson, M.C., Jakab, M., Warfield, S.K., Killiany, R.J., Weiner, H.L., and F.A. Jolesz: Quantitative follow-up of patients with multiple sclerosis using MRI: Reproducibility. J. Magn. Reson. Imaging , 9:509-518, 1999.

172. Kikinis, R., Guttmann, C.R.G., Metcalf, D., Wells III, W.M., Ettinger, G.J., Weiner, H.L., and F.A. Jolesz: Quantitative follow-up of patients with multiple sclerosis using MRI: Technical aspects. J. Magn. Reson. Imaging , 9:519-530, 1999.

173. Balashov, K.E., Rottman, J.B., Weiner, H.L., and W.W. Hancock: CCR5+ and CXCR3+ T cells are increased in multiple sclerosis and their ligands MIP-1a and IP-10 are expressed in demyelinating brain lesions. Proc Natl Acad Sci 96:6873-6878, 1999.

174. Hohol, M.J., Orav, E.J. and Weiner, H.L., Disease steps in multiple sclerosis: a longitudinal study comparing disease steps and EDSS to evaluate disease progression. Mult Scler 5, (5): 349-354, 1999.

175. Maron, R., Melican, N.S., and H.L. Weiner: Regulatory Th2-type T cell lines against insulin and GAD peptides derived from orally- and nasally-treated NOD mice suppress diabetes. J. of Autoimmun. 12:251-258, 1999.

176. Liu, L., Kuchroo, V.K., and H.L. Weiner: B7.2 but not B7.1 costimulation is required for the induction of low dose oral tolerance. J Immunol 163(4) 2284-2290, 1999.

177. Hattori, M., Yamato, E. Itoh, N., Senouku, H., Fujisawa, T., Yoshino, M., Fukuda, M., Matsumoto, E., Toyonaga, T., Nakagawa, I., Petruzzeli, M., McMurray, A., Weiner, H.L., Sagai, T., Moriwaki, K., Shiroishi, T., Maron, R., and T. Lund: Cutting edge: homologous recombination of the MHC class I K region defines new MHC-linked diabetogenic susceptibility gene in nonobese diabetic mice. J Immunol 163(4) 1721-1724, 1999.

178. Khoury, S.J., Orav, E.J, Guttmann, C.R., Kikinis, R., Jolesz, F.A., and H.L. Weiner: Changes in serum levels of ICAM and TNF-R correlate with disease activity in multiple sclerosis. Neurology 11;53(4): 758-764, 1999.

179. Maron, R., Hancock, W.W., Slavin, A., Hattori, M., Kuchroo, V., and H.L. Weiner: Genetic susceptibility or resistance to autoimmune encephalomyelitis in MHC congenic mice is associated with differential production of pro- and anti-inflammatory cytokines. Intl Immun. 11(9): 1573-1580, 1999.

180. Garcia, G., Komagata, Y., Slavin, A.J., Maron, R., and H.L. Weiner: Suppression of collagen induced arthritis by oral or nasal administration of type II collagen. J of Autoimmun. 13, 315-324, 1999.

181. Hohol, M. J., Olek, M. J.et. al.: Treatment of progressive multiple sclerosis with pulse cyclophosphamide/methylprednisolone: response to therapy is linked to the duration of progressive disease. Mult Scler 5, 403-409, 1999.

182. Schwarting, A., Tesch, G., Kinoshita, K., Maron, R., Weiner, H.L., Kelley, V.R. IL-12 drives IFN-gamma-dependent autoimmune kidney disease in MRL- Fas(lpr) mice. J. Immunol. 163:(12): 6884-6891, 1999.

183. Spahn, T.W., Issazadah, S., Salvin, A.J., Weiner, H.L. Decreased severity of myelin oligodendrocyte glycoprotein peptide 33 - 35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain gene. Eur. J. Immunol. 29:4060-4071, 1999.