Howard L. Weiner, M.D.

Principle Investigator

Brigham & Women’s Hospital
Center for Neurologic Diseases
77 Avenue Louis Pasteur - HIM 730
Boston, Massachusetts  02115-5817
United States of America

Office e-mail:   

Office telephone:       (617) 525-5300                       Office fax:  (617) 525-5252

Education:                 1965          B.A.   Dartmouth College, Hanover, New Hampshire
                                    1969          M.D.  University of Colorado School of Medicine

Postdoctoral Training:

Internships and Residencies:

1969–1970   Rotating Intern, Tel Hashomer Hospital, Israel
1970–1971   Medical Resident, Beth Israel Hospital, Boston
1970–1971   Clinical Fellow, Harvard Medical School
1971–1974   Resident in Neurology, Longwood Area Neurology Program
1971–1974   Clinical Fellow in Neurology, Harvard Medical School

Clinical and Research Fellowships:

1972–1974   Research Fellow, Massachusetts General Hospital
                     (Dr. Barry Arnason's laboratory)
1974–1976   Research Fellow, Immunology, University of Colorado Medical Center,
                     Denver, Colorado (Dr. Henry Claman's laboratory)
1974–1976   Special Research Fellow of Colorado Multiple Sclerosis Society

Licensure and Board Certification:
1970                   Massachusetts License Registration
1974                   Colorado License Registration
1978                   American Board of Psychiatry and Neurology

Academic Appointments:

  1976–1977       Instructor in Neurology, Harvard Medical School
  1977–1980       Assistant Professor of Neurology, Harvard Medical School
  1980–1985       Associate Professor of Neurology, Harvard Medical School
  1985–1997       Robert L. Kroc Associate Professor of Neurology, Harvard Medical School
  1997                 Robert L. Kroc Professor of Neurology, Harvard Medical School

Hospital or Affiliated Institution Appointments:

  1984–               Affiliate Member of the Program in Neuroscience, Harvard Medical School
  1977–1987       Associate in Medicine (Neurology), Brigham and Women's Hospital
  1977–1985       Research Associate in Neuroscience, The Children's Hospital
  1987–1991       Physician, Medicine (Neurology), Brigham and Women's Hospital
  1992–               Senior Neurologist, Medicine (Neurology), Brigham and Women’s Hospital

Other Professional Positions & Major Visiting Appointments:

  1977–1989       Annual Intensive Clinical Neurology Course, New York City
  1977–1987       Neuropathology 711, Department of Neuroscience, Harvard Medical School
  1977–               Introduction to Clinical Medicine, Brigham and Women's Hospital
  1977–               Harvard Continuing Education Courses: Neurology, Immunology,
                           Pediatric Neurology, Scientific Foundations of Internal Medicine
  1978–1987       Pathophysiology of the Nervous System—HST 131J
  1981–1983       Lecturer, Neuroimmunology Course,
                           Annual Meeting of the American Academy of Neurology
  1984–1987       Chairman, Neuroimmunology Course,
                           Annual Meeting of the American Academy of Neurology
  1984–               Neurobiology of Disease, Department of Neurobiology, Harvard Medical School
  1988                 Chairman, FASEB Autoimmunity Conference, Saxton's River, VT
  1989                 Co‑Chairman, International Conference on Therapy and Diagnosis of
                           Multiple Sclerosis (National MS Society, Jekyll Island)
  1995                 Co-Chairman, New York Academy of Sciences Conference on Oral Tolerance


Hospital & Health Care Organization Service Responsibilities:

  1976–               Attending physician, Brigham and Women's Hospital Neurology Service
  1976–               Consulting physician, Beth Israel Hospital and Children's Hospital
                           Neurology Services
  1980–1997       Director, Multiple Sclerosis inpatient and outpatient clinical services
                           Brigham and Women's Hospital
  1985–               Co‑Director, Center for Neurologic Diseases, Brigham and Women's Hospital
  1998–               Director, Partners Multiple Sclerosis Center
                           Brigham and Women’s Hospital and Massachusetts General Hospital

Major Committee Assignments:

  1976–               Scientific Advisory Board, Massachusetts Multiple Sclerosis Society
  1980–1983       Clinical Research Center Review Study Section, Ad Hoc Member, NIH
  1982–1987       Scientific Advisory Board, Committee on Research on the Etiology, Diagnosis,
                           Natural History, Prevention and Therapy of Multiple Sclerosis
                           National Multiple Sclerosis Society
  1982–1989       Committee on Working Trials of New Drugs in MS,
                           National Multiple Sclerosis Society
  1983–1985       New Pathways Project, Resource Representative for the
                           Department of Neurology,  Harvard Medical School
  1984                 Virology Study Section, Ad Hoc Member, NIH
  1996                 Advisory Council, National Institute of Allergy and Infectious Diseases,
                           Ad Hoc Member, NIH
  1996–               Advisory Panel, United States Pharmacopeial Convention
  1996                 Committee on Clinical Immunology and Immunopathology, AAI

Professional Societies:

  1976                 American Academy of Neurology
  1976                 American Society for Microbiology
  1976                 American Association for the Advancement of Science
  1977                 American Association of Immunologists
  1981                 American Neurologic Association
  1996                 American Autoimmune Related Diseases Association


Editorial Boards:

2000                Clinical Immunology
2000                Multiple Sclerosis
2000                Journal of Immunology
2000                Journal of Autoimmunity

Awards and Honors:

  1969                 University of Colorado School of Medicine Phi Delta Epsilon Award for Academic Excellence and Merck Award in Medicine
  1974–1976       Research Fellowship, Colorado Multiple Sclerosis Society
  1976–1977       NIH Special Research Fellowship
  1977–1982       NIH Teacher Investigator Award, National Institute of Neurological and Communicative Disorders and Stroke (NINCDS)
  1985                 Recipient of Robert L. Kroc Chair in Neurology for Multiple Sclerosis Research, Awarded by Kroc Foundation, Santa Inez, California
  1988–1995       NIH Jacob Javits Neuroscience Investigator Award (Seven year Merit
                           Award, NINCDS)
2007                John Dystel Prize for Multiple Sclerosis Research, American Academy of Neurology

Major Research Interests:

  • Immunology and immunotherapy of multiple sclerosis
  • Mechanisms of autoimmunity
  • Neuroimmunology
  • Oral tolerance